TFIIE

Composition: Two subunits. Probably a tetramer consisting of two molecules of each subunit.

Features: Large subunit has a zinc finger domain.

Interactions: TFIIE modulates the helicase and kinase activities of TFIIH and the two factors show species-specific interactions.

Functions: Recruits TFIIH to the initiation complex and modulates TFIIH kinase and helicase activities. Appears to be required for escape of the RNA polymerase into elongation mode (promoter clearance).

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Select Database: GenBank GenBank Updates Both
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Locus Definition Accession No. NID Keywords
Source Reference Comment Features

Rev. 06/27/96

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Copyright Steve Buratowski