TFIIF

Composition: Two subunits (yeast has a third non-essential protein associated).

Features:

Interactions: TFIIF binds directly to RNA polymerase II (and was originally isolated as an RNA polymerase II associated protein or RAP). TFIIF is necessary for RNA polymerase II to stably associate with the TFIIF-TFIIB-promoter complex. There is a protein interaction between the small subunit and TFIIB in vitro and a genetic interaction between the large subunit and TFIIB.

Functions: Helps recruit RNA polymerase II to the initiation complex in collaboration with TFIIB. TFIIF is a component of the yeast holoenzyme and mediator complexes. Promotes transcription elongation, may remain associated with the elongating polymerase.

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Select Database: GenBank GenBank Updates Both
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Locus Definition Accession No. NID Keywords
Source Reference Comment Features

Rev. 06/27/96

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Copyright Steve Buratowski